Question:medium

Most diffusible ion across the cell membrane is?

Show Hint

Compare the cations with the chief diffusible anion of the body.
Updated On: Jun 24, 2026
  • Na+
  • K+
  • Cl-
  • None
Show Solution

The Correct Option is C

Solution and Explanation

Step 1: Diffusion across the membrane depends on how well a solute dissolves in the fatty interior of the bilayer. The better the lipid solubility, the higher the permeability.

Step 2: Ions face a barrier because of their charge and hydration shell, so all of them cross slowly compared with gases. But among ions themselves there is a ranking.

Step 3: Chloride moves through the membrane more freely than the cations sodium and potassium. Sodium is actively excluded by the Na-K pump, and potassium sits between the two. Comparing the three, chloride shows the greatest passive movement.

Step 4: So the single ion that diffuses most across the membrane is chloride.

\[\boxed{\text{Cl}^-}\]
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