Question

Match the hypersensitivity type with its example. 

• A. A-3, B-1, C-2, D-4
• B. A-1, B-3, C-4, D-2
• C. A-3, B-2, C-1, D-4
• D. A-4, B-1, C-2, D-3

Hint:

Remember the acronym \textbf{ACID} for hypersensitivity types: \textbf{A}llergic (Type I), \textbf{C}ytotoxic (Type II), \textbf{I}mmune complex (Type III), \textbf{D}elayed (Type IV).

Answer 1

The Correct Option is A

In immunology, hypersensitivity is classified into four types based on the mechanism and timing of the immune response. Let's match each type with its example:

1. Type I Hypersensitivity: Also known as immediate hypersensitivity, it is mediated by IgE antibodies. Common examples include allergies such as those to pollen, dust mites, or certain foods.
2. Type II Hypersensitivity: This involves IgG or IgM antibodies directed against cell surface or matrix antigens. Conditions like Myasthenia gravis fall into this category.
3. Type III Hypersensitivity: Also known as immune complex-mediated hypersensitivity. This occurs when immune complexes are deposited in various tissues, leading to conditions like Serum sickness.
4. Type IV Hypersensitivity: Also known as delayed-type hypersensitivity (DTH). It is mediated by T-cells rather than antibodies. An example is Contact dermatitis, which occurs upon exposure to substances like poison ivy.

Based on these explanations, the correct match is:

• A-3: Type I - Allergy
• B-1: Type II - Myasthenia gravis
• C-2: Type III - Serum sickness
• D-4: Type IV - Contact dermatitis

Thus, the correct answer is A-3, B-1, C-2, D-4.