Question

Match the following disease with their test for detection:

Disease		Diagnostic tests
P.	Tuberculosis	(i)	Lepromin test
Q.	AIDS	(ii)	ELISA
R.	Syphilis	(iii)	Mantoux test
S.	Leprosy	(iv)	Kahn's test

• A. P(iv), Q(ii), R (iii), S(i)
• B. P(iii), Q(ii), R (iv), S(i)
• C. P(i), Q(ii), R (iii), S(iv)
• D. P(ii), Q(i), R (iii), S(iv)

Answer 1

The Correct Option is B

Step 1: Understanding the Question:
We need to pair four diseases, tuberculosis, AIDS, syphilis, and leprosy, with the correct diagnostic test for each.

Step 2: Key Concept:
Each of these diseases has one classic, well-known confirmatory or screening test taught in microbiology: tuberculosis uses the Mantoux (tuberculin) skin test, AIDS is screened using ELISA for HIV antibodies, syphilis uses the Kahn flocculation test, and leprosy uses the lepromin skin test to gauge immune response.

Step 3: Detailed Explanation:
Matching P (Tuberculosis) with (iii) Mantoux test is correct, since this skin test checks for prior exposure to Mycobacterium tuberculosis. Matching Q (AIDS) with (ii) ELISA is correct, since ELISA is the routine screening test for HIV antibodies. Matching R (Syphilis) with (iv) Kahn's test is correct, since this is a classic serological flocculation test for syphilis. Matching S (Leprosy) with (i) Lepromin test is correct, since this test measures cell-mediated immunity against Mycobacterium leprae.

Step 4: Final Answer:
The correct set of pairs is P(iii), Q(ii), R(iv), S(i).