Question

Match the following \[ \begin{array}{|c|l|c|l|} \hline & Disease / Application & & Molecular basis / Use \hline A & \text{Sickle cell anemia} & I & \text{Frameshift mutation} B & \text{Thalassemia} & II & \text{Missense point mutation} C & \text{Duchenne muscular dystrophy} & III & \beta\text{-globin gene defect} D & \text{PCR} & IV & \text{DNA amplification technique} \hline \end{array} \] The correct matching is

• A. A -- II, B -- III, C -- I, D -- IV
• B. A -- III, B -- II, C -- I, D -- IV
• C. A -- II, B -- I, C -- III, D -- IV
• D. A -- I, B -- III, C -- II, D -- IV

Hint:

Remember: \[ \boxed{ \begin{aligned} \text{Sickle cell anemia} &\rightarrow \text{Missense mutation} \text{Thalassemia} &\rightarrow \beta\text{-globin defect} \text{Duchenne muscular dystrophy} &\rightarrow \text{Frameshift mutation} \text{PCR} &\rightarrow \text{DNA amplification} \end{aligned} } \]

Answer 1

The Correct Option is A