Match the enzymes with their functions in DNA replication:
| List I | List II |
|---|---|
| A. Topoisomerase --- III. Helps to relieve the twisting strain ahead of the replication fork B. Helicases --- I. Unwinds the double helix at the replication fork, separating the parental strands C. DNA polymerase --- IV. Catalyzes the synthesis of new DNA by adding nucleotides D. DNA ligase --- II. Joining the sugar phosphate backbones of all the Okazaki fragments | III. Helps to relieve the twisting strain ahead of the replication fork I. Unwinds the double helix at the replication fork, separating the parental strands IV. Catalyzes the synthesis of new DNA by adding nucleotides II. Joining the sugar phosphate backbones of all the Okazaki fragments |
| LIST I | LIST II |
|---|---|
| A. Ligase | I. Reduce topological strain |
| B. Helicase | II. Adds phosphate group |
| C. Gyrase | III. Joins two open ends of DNA |
| D. Kinase | IV. Unwinds the DNA |