Question

Match LIST-I with LIST-II

Choose the correct answer from the options given below:

• A. A - IV, B - III, C - I, D - II
• B. A - IV, B - III, C - II, D - I
• C. A - I, B - II, C - IV, D - III
• D. A - III, B - IV, C - I, D - II

Hint:

Remember the key players in E. coli replication: DnaA (initiator), DnaB (Helicase), DnaC (loader), DnaG (Primase), and Pol III (main polymerase). Pol I (`polA`) is famous for primer removal, and Pol II (`polB`) is for repair.

Answer 1

The Correct Option is B

Step 1: Concept Overview:
The question requires matching *E. coli* DNA replication genes (LIST-I) to their corresponding protein products or functions (LIST-II).
Step 2: Detailed Solution:
Matching each gene to its product/function:


A. *polA*: Encodes DNA polymerase I, involved in DNA repair and RNA primer removal. Matches IV. DNA polymerase I.

B. *polB*: Encodes DNA polymerase II, primarily for DNA repair. Matches III. DNA polymerase II.

C. *DnaG*: Encodes Primase, which synthesizes RNA primers to initiate DNA synthesis. Matches II. Primase.

D. *DnaB & C*: DnaB is the main replicative Helicase in *E. coli*, unwinding the DNA helix. DnaC is the helicase loader, placing DnaB at the origin of replication (OriC). The complex provides helicase activity at the origin. Matches I. Helicase at OriC.

Step 3: Conclusion:
The correct matches are: A-IV, B-III, C-II, D-I, corresponding to option (B).