Question

Match LIST-I with LIST-II
\begin{tabularx}{0.8\textwidth}{|l|X|l|X|} \hline \multicolumn{2}{|c|}{LIST-I} & \multicolumn{2}{c|}{LIST-II}
\multicolumn{2}{|c|}{Mitochondrial Compartments} & \multicolumn{2}{c|}{Enzymes present}
\hline A. & Matrix & I. & ATP synthetase
B. & Inner membrane & II. & Monoamine oxidase
C. & Space between inner and outer membranes & III. & Citrate synthetase
D. & Outer membrane & IV. & Adenylate kinase
\hline \end{tabularx}
Choose the most appropriate answer from the options given below:

• A. A - IV, B - II, C - III, D - I
• B. A - III, B - I, C - IV, D - II
• C. A - II, B - I, C - IV, D - III
• D. A - I, B - IV, C - III, D - II

Hint:

Associate the main function with the compartment to remember enzyme locations:

\textbf{Matrix} \(\rightarrow\) Krebs Cycle \(\rightarrow\) Citrate Synthetase.
\textbf{Inner Membrane} \(\rightarrow\) ATP Production \(\rightarrow\) ATP Synthase.
\textbf{Outer Membrane} \(\rightarrow\) Acts as a boundary, has specific enzymes like Monoamine Oxidase.
\textbf{Intermembrane Space} \(\rightarrow\) "In-between" reactions \(\rightarrow\) Adenylate Kinase. \end{itemize}

Answer 1

The Correct Option is B

Step 1: Concept Summary:
Mitochondria, organelles with double membranes, possess compartments with specific enzymes for cellular respiration and metabolism. This question assesses understanding of mitochondrial enzyme localization.

Step 2: Detailed Explanation:
Matching mitochondrial compartments to their enzymes:
- A. Matrix: The innermost compartment, the matrix, is where the Krebs cycle (citric acid cycle) and fatty acid oxidation occur. Citrate synthase, catalyzing the first step of the Krebs cycle, resides in the matrix. (A \(\rightarrow\) III).
- B. Inner membrane: Folded into cristae, this membrane hosts the electron transport chain and oxidative phosphorylation. ATP synthase (or Complex V) is located in the inner membrane, using the proton gradient for ATP production. (B \(\rightarrow\) I).
- C. Intermembrane space: This space contains enzymes utilizing ATP from the matrix. Adenylate kinase, a phosphotransferase, catalyzes \(2 \text{ ADP} \rightleftharpoons \text{ATP} + \text{AMP}\) here. (C \(\rightarrow\) IV).
- D. Outer membrane: Permeable, the outer membrane contains enzymes like Monoamine oxidase, involved in neurotransmitter breakdown. (D \(\rightarrow\) II).

Step 3: Conclusion:
The correct matches are A-III, B-I, C-IV, D-II, corresponding to option (B).