Question:medium

Match List-I with List-II:

Show Hint

Down syndrome is the most common human trisomy (chromosome 21).
  • (A)-(IV), (B)-(II), (C)-(III), (D)-(I)
  • (A)-(I), (B)-(II), (C)-(III), (D)-(IV)
  • (A)-(I), (B)-(II), (C)-(IV), (D)-(III)
  • (A)-(III), (B)-(IV), (C)-(I), (D)-(II)
Show Solution

The Correct Option is A

Solution and Explanation

Step 1: Nullisomy is \( 2n - 2 \), loss of a full chromosome pair.
Step 2: Trisomy is \( 2n + 1 \) and Monosomy is \( 2n - 1 \).
Step 3: Tetrasomy is \( 2n + 2 \), gain of a full extra pair.
\[ \boxed{\text{(A)-(IV), (B)-(II), (C)-(III), (D)-(I)}} \]
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