Question

Match List I (Cells) with List II (Tumours that develop from them) and select the correct answer using the codes given below the lists.

List I (Cells)	List II (Tumours that develop from them)
A. Leydig cells	1. Carcinoid tumour
B. B cells	2. Medullary carcinoma
C. Parafollicular cells	3. Interstitial cell tumour
D. Argentaffin cells	4. Insulinoma

• A. A-1, B-4, C-2, D-3
• B. A-3, B-2, C-1, D-4
• C. A-1, B-2, C-4, D-3
• D. A-3, B-4, C-2, D-1

Hint:

Match each cell to the tumour that carries its own name, such as interstitial cell tumour for Leydig cells.

Answer 1

The Correct Option is D

This question tests whether you know which tumour arises from which named cell type, then asks you to pick the code that lines them up correctly.

1. Leydig cells: These are the testosterone producing cells of the testis, also called interstitial cells. A tumour built from them is named an interstitial cell tumour, so A goes with 3.
2. B cells: These are the insulin secreting cells of the pancreatic islets. A tumour of these cells that oversecretes insulin is an insulinoma, so B goes with 4.
3. Parafollicular cells: Also called C cells of the thyroid, these make calcitonin. Their tumour is medullary carcinoma of the thyroid, so C goes with 2.
4. Argentaffin cells: These serotonin containing cells of the gut give rise to carcinoid tumours, so D goes with 1.

Putting these together gives A-3, B-4, C-2, D-1, which is exactly what code (d) states.

Let's summarize:

• Interstitial cell tumour is simply the Leydig cell tumour of the testis under another name.
• Insulinoma, medullary carcinoma, and carcinoid tumour are the classic tumours of B cells, C cells, and argentaffin cells respectively.

So the matching code that fits is (d), A-3, B-4, C-2, D-1.