Question:hard

Low CSF protein may be seen in all of the following conditions, except:

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Myxedema raises CSF protein, it does not lower it.
Updated On: Jun 24, 2026
  • Recurrent lumbar puncture
  • Hypothyroidism
  • Pseudotumor cerebri
  • Infants
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The Correct Option is B

Solution and Explanation

Frame it as: which option breaks the low-protein pattern. Draining the subarachnoid space repeatedly, as with frequent taps or a persistent leak, removes protein-rich fluid quicker than it can be made, dropping the protein level. Idiopathic intracranial hypertension, the pseudotumor cerebri picture, is the high-pressure but normal-to-low protein syndrome, so it fits the low side. Infants are commonly grouped among the low CSF protein states. Hypothyroidism does the opposite: myxedema is a textbook cause of a raised CSF protein, sitting alongside conditions like Guillain Barre and acoustic neuroma in that elevated-protein list. Since the stem wants the one that is not low, the thyroid-deficiency state is the outlier. \[\boxed{\text{Hypothyroidism}}\]
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