Question:medium
Ketone body formation without glycosuria is seen in?
Ketone body formation without glycosuria is seen in?
Show Hint
Starvation gives ketosis with low-normal glucose and no urine sugar; DM has glycosuria.
Updated On: Jun 24, 2026
- Diabetes mellitus
- Diabetes insipidus
- Starvation
- Obesity
Show Solution
The Correct Option is C
Solution and Explanation
Step 1: Two findings must coexist: ketone bodies present, but the urine free of glucose. We screen each option against that pair.
Step 2: Uncontrolled diabetes mellitus certainly makes ketones, however the high blood glucose overflows into urine, so glycosuria is the rule. That breaks the condition and rules out option a.
Step 3: Diabetes insipidus is purely an ADH or renal water-handling problem producing dilute polyuria; it neither drives ketosis nor causes glycosuria. Obesity by itself also fails to generate meaningful ketosis. Both are out.
Step 4: During prolonged fasting, insulin falls and fatty acids flood the liver to be turned into ketone bodies, while gluconeogenesis keeps blood sugar low to normal. Result: ketosis with Rothera positive but Benedict negative urine, exactly ketosis without glycosuria.
\[\boxed{\text{Starvation}}\]
Step 2: Uncontrolled diabetes mellitus certainly makes ketones, however the high blood glucose overflows into urine, so glycosuria is the rule. That breaks the condition and rules out option a.
Step 3: Diabetes insipidus is purely an ADH or renal water-handling problem producing dilute polyuria; it neither drives ketosis nor causes glycosuria. Obesity by itself also fails to generate meaningful ketosis. Both are out.
Step 4: During prolonged fasting, insulin falls and fatty acids flood the liver to be turned into ketone bodies, while gluconeogenesis keeps blood sugar low to normal. Result: ketosis with Rothera positive but Benedict negative urine, exactly ketosis without glycosuria.
\[\boxed{\text{Starvation}}\]
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