Question

Increased LH : FSH ratio is found in

• A. Premature menopause
• B. Sheehan syndrome
• C. Polycystic ovary syndrome
• D. Turner's syndrome

Hint:

Ask which condition raises LH more than FSH, not the other way round.

Answer 1

The Correct Option is C

This question is about a hormone ratio: which condition among the four raises LH above FSH rather than the other way round.

1. Premature menopause: the ovaries stop working early, inhibin B falls sharply, and the pituitary responds by pushing FSH up more than LH. That gives a high FSH:LH ratio, the opposite of what the question asks.
2. Sheehan syndrome: this is pituitary failure after heavy blood loss during childbirth. Both LH and FSH drop because the gland making them is damaged, so neither hormone is raised.
3. Polycystic ovary syndrome: here the ovaries work but the brain sends GnRH pulses in a fast pattern that favors LH secretion. LH climbs while FSH stays low or normal, so the LH:FSH ratio goes up, often past 2:1 or even 3:1.
4. Turner's syndrome: the ovaries are streaks that barely function, so like premature menopause, inhibin B is very low and FSH rises more than LH, again a high FSH:LH pattern, not high LH:FSH.

Only PCOS matches a raised LH:FSH ratio, since the other three conditions either lower both hormones or raise FSH ahead of LH. The paper's printed key marks Turner's syndrome, but that pairs with a high FSH:LH ratio, so on medical grounds the answer here is corrected to PCOS.

Let's summarize:

• Ovarian failure states (premature menopause, Turner's syndrome) raise FSH more than LH.
• Sheehan syndrome lowers both hormones.
• PCOS is the one condition where LH outruns FSH, giving the classic raised LH:FSH ratio.

So the corrected answer is polycystic ovary syndrome.