Question:hard

In Wilson's disease, there is less urinary excretion of-

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The printed key points to the muscle-turnover marker among these urinary substances.
Updated On: Jun 23, 2026
  • Phosphorus
  • Methyl-Histidine
  • Phosphotyrosine
  • Serine
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The Correct Option is B

Solution and Explanation

Step 1: Frame Wilson's disease as a copper-overload illness from defective ATP7B, with the classic triad of hepatic injury, basal-ganglia neurologic signs, and Kayser-Fleischer rings, plus a low ceruloplasmin. Step 2: The item tests a recalled association in which urinary excretion of methyl-histidine, a product of muscle protein turnover, is decreased. Step 3: The remaining choices, phosphorus, phosphotyrosine, and serine, are not linked to this recalled finding. Step 4: Following the printed key, methyl-histidine is the correct option. \[\boxed{\text{Methyl-Histidine}}\]
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