Self-fertilization, or selfing, represents the most intense form of inbreeding. During each selfing generation, heterozygosity is reduced by half. For instance, an initially 100% heterozygous (Aa) population will yield 25% AA, 50% Aa, and 25% aa offspring after one generation of selfing. Consequently, heterozygosity decreases from 100% to 50%, demonstrating a heterozygosity loss of 1/2 per generation.