Question:medium

In Human Genome Project (HGP) the method of identifying whole set of genome contained all coding and non-coding regions is referred as:

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Annotation = Putting labels on the entire genome map.
Updated On: Jun 6, 2026
  • Expressed sequence tags
  • Single nucleotide polymorphism
  • Sequence Annotation
  • Electrophoresis
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The Correct Option is C

Solution and Explanation

Step 1: What the question asks.
In the Human Genome Project, we want the name of the method that maps the whole genome, both coding and non-coding parts.

Step 2: Meaning of annotation.
Once the DNA sequence is read, scientists go through it and label what each region is, where the genes are, where the regulatory and non-coding stretches lie. This labelling of the full set is called sequence annotation.

Step 3: Why ESTs do not fit.
Expressed sequence tags only look at genes that are actually transcribed (the coding, expressed regions). They skip the non-coding parts, so they cannot map the whole genome.

Step 4: Why the other options do not fit.
Single nucleotide polymorphism is about single-base differences between people. Electrophoresis is just a lab technique to separate DNA fragments by size. Neither names the whole-genome mapping approach.

Step 5: Conclusion.
Therefore the correct answer is "Sequence Annotation". \[ \boxed{\text{Sequence Annotation}} \]
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