Notice the symmetry of the exponents in binomial boundaries! For $X = 0$, the value is simply $q^n$, and for $X = n$, the value is simply $p^n$. Since $q^4 = (2/3)^4$, its complement must be $p = 1/3$. Raising that to the fourth power gives $\frac{1}{81}$ in one quick step!