If by increasing the quantity of input $X_1$ by one unit, the farmer can give up two units of input $X_2$ and still produce the same output, then the $MRS_{X1,X2}$ is:
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The subscript order $MRS_{A, B}$ represents the amount of input B we are willing to substitute/give up per unit of input A gained. Thus, it is simply $\text{units of B given up} / \text{units of A added}$.