For a line forming angles \( \alpha, \beta, \gamma \) with the coordinate axes, the relation \( \cos^2 \alpha + \cos^2 \beta + \cos^2 \gamma = 1 \) is universally applicable, reflecting the fundamental property of direction cosines. Conversely, the expression \( \cos \alpha + \cos \beta + \cos \gamma = 1 \) is not generally valid as it implies a particular orientation not characteristic of direction cosines.
Final Answer: \( \boxed{ {(D)}} \)