Question

Identify the cells whose secretion protects the lining of gastro-intestinal tract from various enzymes.

• A. Chief Cells
• B. Goblet Cells
• C. Oxyntic Cells
• D. Duodenal Cells

Answer 1

The Correct Option is B

The question asks us to identify which cells protect the lining of the gastrointestinal tract from various enzyme secretions. Let's analyze the options:

• Chief Cells: These cells, located in the stomach, secrete pepsinogen, which is a precursor to pepsin, an enzyme that digests proteins. They do not play a role in protecting the gastrointestinal lining.
• Goblet Cells: These are specialized epithelial cells found throughout the gastrointestinal tract. They secrete mucus, which forms a protective layer on the mucosal surfaces. This mucus acts as a barrier between the lining of the gastrointestinal tract and the harsh acidic environment, as well as digestive enzymes, thereby protecting the epithelium. These cells are indeed responsible for the protection of the lining of the gastrointestinal tract.
• Oxyntic Cells: Also known as parietal cells, they secrete hydrochloric acid (HCl) in the stomach. They play a role in digestion by helping break down food and kill bacteria but are not involved in protecting the stomach lining.
• Duodenal Cells: These refer to cells in the duodenum, the first part of the small intestine, but this is not a specific cell type known for protection against enzymes.

From this analysis, we can conclude that the cells which secrete substances that protect the lining of the gastrointestinal tract from various enzymes are the Goblet Cells.

Therefore, the correct answer is Goblet Cells.