Question

Hybridoma cells are

• A. only cells having oncogenes
• B. product of spore formation in bacteria
• C. nervous cells of frog
• D. hybrid cells resulting from myeloma cells.

Answer 1

The Correct Option is D

Hybridoma cells are a crucial concept in the field of immunology and biotechnology. Let's explore step-by-step to understand what hybridoma cells are and why the correct option is "hybrid cells resulting from myeloma cells."

1. Hybridoma Technology: This technology is used to produce large quantities of monoclonal antibodies. The process involves the fusion of specific types of cells.
2. Creation of Hybridoma Cells: These cells are created by fusing an antibody-producing B-cell with a myeloma cell, which is a type of cancer cell.
3. Role of Myeloma Cells: Myeloma cells are used in this process because they have the ability to divide indefinitely. This trait is crucial as it endows the hybrid cells with the capacity for continuous division, thus producing large quantities of antibodies.
4. Characteristics of Hybridoma Cells: The resulting hybridoma cells combine the desirable traits of both parent cells - the immortality of myeloma cells and the specific antibody production ability of B-cells.
5. Why Other Options are Incorrect:
   • "Only cells having oncogenes": While myeloma cells (cancer cells) do contain oncogenes, hybridoma cells are specifically the result of fusion with B-cells.
   • "Product of spore formation in bacteria": This is unrelated to hybridoma technology, which involves animal cells, not bacterial spore formation.
   • "Nervous cells of frog": This option is completely unrelated to the concept of hybridoma cells.
6. Conclusion: Thus, the accurate description for hybridoma cells is that they are "hybrid cells resulting from myeloma cells."