Question:medium

Human chromosome 2, a large metacentric chromosome is the result of ___________ during the course of evolution. 
 

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Remember the key evidence: Humans have 46 chromosomes, chimps have 48. The fusion of two ape chromosomes created our chromosome 2. This specific type of fusion of two chromosomes at the centromere is called a Robertsonian translocation.
Updated On: Feb 18, 2026
  • Translocation
  • Robertsonian translocation
  • Chromosomal replication
  • Chromosomal elongation
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The Correct Option is B

Solution and Explanation

Step 1: Concept Overview:
The question concerns the chromosomal event in human evolution that resulted in human chromosome 2. Humans possess 23 chromosome pairs, while great apes like chimpanzees have 24. This difference arises from a chromosome fusion.
Step 2: Detailed Explanation:
- Cytogenetic data reveals that human chromosome 2 corresponds to two separate chromosomes in other great apes.
- The hypothesis suggests that, within the human lineage, two ancestral acrocentric chromosomes fused at their ends, creating the large, metacentric human chromosome 2.
- This specific fusion of two acrocentric chromosomes at or near their centromeres is termed a Robertsonian translocation. Evidence includes a non-functional centromere remnant and telomeric sequences (typically at chromosome ends) within human chromosome 2.
- "Translocation" is a broad term; "Robertsonian translocation" specifically describes this event. "Chromosomal replication" and "elongation" are incorrect.
Step 3: Conclusion:
The emergence of human chromosome 2 exemplifies a Robertsonian translocation in evolution.
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