Question:medium

HPV is responsible mainly for:

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HPV-16 and HPV-18 together cause more than 70% of cervical cancers worldwide.
Updated On: Mar 11, 2026
  • Ovarian Cancer
  • Prostate Cancer
  • Liver Cancer
  • Cervical Cancer
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The Correct Option is D

Solution and Explanation

Step 1: Understanding HPV.
Human Papillomavirus (HPV) is a DNA virus. High-risk strains like HPV-16 and HPV-18 are linked to cancer development.
Step 2: Oncogenic mechanism.
HPV produces E6 and E7 proteins that inactivate tumor suppressor proteins p53 and Rb. This results in uncontrolled cell growth and cancer.
Step 3: Identifying the main cancer.
- HPV causes nearly all cervical cancers globally.
- While it can cause anal, oropharyngeal, and penile cancers, cervical cancer is the primary associated disease.
Step 4: Excluding other options.
- (A) Ovarian cancer: Not associated with HPV.
- (B) Prostate cancer: No proven HPV link.
- (C) Liver cancer: Primarily linked to Hepatitis B and C, not HPV.
Final Answer:
\[\boxed{\text{Cervical Cancer}}\]
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