Question:easy
Glucose is transported in renal tubular cells by?
Glucose is transported in renal tubular cells by?
Show Hint
SGLT1 and SGLT2 move Na and glucose in the same direction = cotransport.
Updated On: Jun 24, 2026
- K symport
- K antiport
- Na antiport
- Na cotransport
Show Solution
The Correct Option is D
Solution and Explanation
Step 1: The renal proximal tubule recovers filtered glucose almost completely, and the molecular machinery for this is the SGLT family on the brush-border membrane.
Step 2: SGLT2 (high capacity, early tubule) and SGLT1 (high affinity, later tubule) couple the inward flow of sodium to the inward flow of glucose. Because both species cross in the same direction, the process is a cotransport, also called symport.
Step 3: The energy is indirect: the sodium gradient created by the basolateral sodium pump provides the driving force, classifying this as secondary active transport. A potassium symport or any antiport mechanism for glucose simply does not exist here, so options (a), (b) and (c) are excluded.
Step 4: The correct mechanism is sodium-glucose cotransport.
\[\boxed{\text{Na cotransport}}\]
Step 2: SGLT2 (high capacity, early tubule) and SGLT1 (high affinity, later tubule) couple the inward flow of sodium to the inward flow of glucose. Because both species cross in the same direction, the process is a cotransport, also called symport.
Step 3: The energy is indirect: the sodium gradient created by the basolateral sodium pump provides the driving force, classifying this as secondary active transport. A potassium symport or any antiport mechanism for glucose simply does not exist here, so options (a), (b) and (c) are excluded.
Step 4: The correct mechanism is sodium-glucose cotransport.
\[\boxed{\text{Na cotransport}}\]
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