Question

Given below are two statements
Statement I : RNA interference takes place in all Eukaryotic organisms as method of cellular defense.
Statement II : RNAi involves the silencing of a specific mRNA due to a complementary single-stranded RNA molecule that binds and prevents translation of mRNA
In the light of the above statements, choose the correct answer from the options given below

• A. Statement I is true but Statement II is false.
• B. Statement I is false but Statement II is true.
• C. Both Statement I and Statement II are true.
• D. Both Statement I and Statement II are false.

Answer 1

The Correct Option is A

Statement I: RNA interference (RNAi) is a cellular defense mechanism in eukaryotes against viruses and foreign genetic material, also regulating gene expression. Thus, Statement I is true.
Statement II: RNAi silences mRNA using double-stranded RNA (dsRNA), not single-stranded RNA (ssRNA). dsRNA is processed into small interfering RNAs (siRNAs). These siRNAs guide the RNA-induced silencing complex (RISC) to target mRNA, where RISC cleaves the mRNA for degradation, preventing translation.
Thus, statement II is false.