Question

Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): In the early part of the twentieth century, 2,4-Dinitrophenol (DNP) was prescribed as a “diet pill” for weight loss.
Reason (R): The DNP reduces metabolic rate by uncoupling oxidative phosphorylation from electron transport.
In light of the above statements, choose the correct answer from the options given below:

• A. Both (A) and (R) are true and (R) is the correct explanation of (A).
• B. Both (A) and (R) are true but (R) is NOT the correct explanation of (A).
• C. (A) is true but (R) is false.
• D. (A) is false but (R) is true.

Hint:

Uncoupling agents like DNP, FCCP, and thermogenin (in brown adipose tissue) always increase oxygen consumption and metabolic rate while decreasing the efficiency of ATP synthesis, producing significant heat.

Answer 1

The Correct Option is C