Question

Given below are two statements, one is labelled as Assertion (A) and other one labelled as Reason (R).
Assertion (A): Tetracyclines inhibit protein synthesis and exhibit broad spectrum bactericidal effect.
Reason (R): Tetracyclines bind to 30 S subunit and inhibit the binding of aminoacyl-tRNA to A-site.
In light of the above statements, choose the correct answer from the options given below.

• A. Both (A) and (R) are true and (R) is the correct explanation of (A).
• B. Both (A) and (R) are true but (R) is NOT the correct explanation of (A).
• C. (A) is true but (R) is false.
• D. (A) is false but (R) is true.

Hint:

A classic exam trap is confusing bacteriostatic and bactericidal drugs:
Bacteriostatic: Tetracyclines, Macrolides, Sulfonamides, Chloramphenicol.
Bactericidal: Penicillins, Cephalosporins, Aminoglycosides, Fluoroquinolones.

Answer 1

The Correct Option is D