Question:medium

Given below are two statements marked Assertion and Reason.
Assertion: Individuals with Klinefelter syndrome lose their secondary sexual characters and develop gynaecomastia.
Reason: The presence of the XYY chromosomal pattern leads to underdeveloped testes and reduced testosterone levels in affected males.

Show Hint

Klinefelter = XXY; Turner = XO. These are the most commonly tested syndromes.
Updated On: Mar 10, 2026
  • Both Assertion and Reason are true and Reason is the correct explanation for Assertion.
  • Both Assertion and Reason are true but Reason is not the correct explanation for Assertion.
  • Assertion is true and Reason is false.
  • Both Assertion and Reason are false.
Show Solution

The Correct Option is C

Solution and Explanation

To solve the given question about Klinefelter syndrome and the chromosomal patterns, let's analyze both the assertion and the reason provided.

  1. Understanding the Assertion:
    • Assertion: "Individuals with Klinefelter syndrome lose their secondary sexual characters and develop gynaecomastia."
    • Klinefelter syndrome is a genetic condition that affects males, characterized by the presence of an extra X chromosome (XXY pattern), not XYY.
    • Men with this condition typically possess underdeveloped testes, which leads to reduced levels of testosterone.
    • The reduction in testosterone can result in the loss of secondary sexual characteristics like facial and body hair, deep voice, and also lead to the development of gynaecomastia (breast tissue).
    • Thus, the assertion is true.
  2. Analyzing the Reason:
    • Reason: "The presence of the XYY chromosomal pattern leads to underdeveloped testes and reduced testosterone levels in affected males."
    • The XYY chromosomal pattern is generally associated with a genetic condition known as "XYY syndrome" or "47,XYY syndrome."
    • Unlike Klinefelter's syndrome, XYY syndrome does not typically result in hormonal imbalances or characteristics such as gynaecomastia. Males with XYY syndrome are usually phenotypically normal but may be taller than average.
    • Therefore, the reason connecting reduced testosterone and underdeveloped testes to the XYY pattern is incorrect.
    • Hence, the reason is false.

Conclusion: Since the assertion is true and the reason is false, the correct answer is: Assertion is true and Reason is false.

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