Question

Genetic engineering has been successfully used for producing

• A. Transgenic models for studying new treatments for certain cardiac diseases
• B. Transgenic Cow ? Rosie which produces high fat milk for making ghee
• C. Animals like bulls for farm work as they have super power
• D. Transgenic mice for testing safety of the polio vaccine before use in humans

Answer 1

The Correct Option is D

Genetic engineering is a scientific technique utilized to modify the genomes of living organisms through biotechnology. This modification aims to add or alter specific traits that can be beneficial for various applications in medicine, agriculture, and research.

To address the given question, let's explore each option presented:

• Transgenic models for studying new treatments for certain cardiac diseases: While transgenic models are used to study a wide range of diseases, the question is specific about certain applications. This isn't a direct example of genetic engineering in terms of historical significance or commonality.
• Transgenic Cow - Rosie which produces high fat milk for making ghee: The transgenic cow named Rosie is known to produce milk containing human proteins such as alpha-lactalbumin, rather than high fat milk for making ghee. This option contains inaccuracies about Rosie's genetic engineering purpose.
• Animals like bulls for farm work as they have super power: The creation of animals like bulls with "super power" isn't a documented or realistic application of current genetic engineering. Genetic engineering focuses more on specific genetic traits rather than broad enhancements like "super power."
• Transgenic mice for testing the safety of the polio vaccine before use in humans: This is precisely a significant application of genetic engineering. Transgenic mice have been genetically modified, for example, by adding human genes so that they closely mimic human response systems. This makes them perfect models for preclinical testing, including vaccine safety trials like those for the polio vaccine.

Conclusion: The correct answer is "Transgenic mice for testing safety of the polio vaccine before use in humans." This is a well-established application of genetic engineering that has proven vital in medical research and vaccine development, providing a safer and more ethical means to perform initial testing.

Through this step-by-step analysis, we identify the vital role of genetic engineering in biomedical research with significant contributions to vaccine testing, especially the safety trials of the polio vaccine using transgenic mice.