Question

Function of telomeres in nucleus:

• A. Pole ward movement
• B. To initiate the RNA synthesis
• C. To seal the ends of chromosome
• D. To recognize the homologous chromosome

Answer 1

The Correct Option is C

The function of telomeres in the nucleus is primarily to seal the ends of chromosomes. Let's understand this function in detail:

1. Telomeres Structure: Telomeres are repetitive nucleotide sequences found at the ends of linear chromosomes in most eukaryotic organisms. They consist of non-coding DNA associated with specific proteins, forming a cap-like structure at each chromosome end.
2. Function: The main function of telomeres is to protect the chromosome ends from degradation and from being recognized as double-strand breaks by the DNA repair machinery. This protection is crucial as it prevents chromosomes from fusing with each other or rearranging, which can lead to genomic instability and diseases such as cancer.
3. Sealing Ends: Telomeres "seal" the chromosome ends, allowing cells to distinguish between normal chromosome termini and DNA breaks. This distinguishes them from options like initiating RNA synthesis or recognizing homologous chromosomes, as telomeres do not perform these functions.
4. Importance in Cell Division: During DNA replication, the enzymes that duplicate DNA cannot replicate the very end of chromosomes. As a result, telomeres shorten with each cell division, which is a normal part of aging and cellular lifespan regulation.

Therefore, the correct answer is: To seal the ends of chromosome.