Question:medium

First line of treatment of mastitis in a lactating mother is

Updated On: Jun 23, 2026
  • Dicloxacillin
  • Cefazolin
  • Ceftriaxone
  • Ampicillin
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The Correct Option is A

Solution and Explanation

Step 1: Infective mastitis during lactation is overwhelmingly a Staphylococcus aureus problem, and most of these strains make penicillinase that inactivates ordinary penicillins.
Step 2: The drug must resist that enzyme and be acceptable during breastfeeding. Penicillinase-resistant penicillins such as dicloxacillin fit both requirements and are the standard first agent; cephalexin or clindamycin serve those allergic to penicillin.
Step 3: Plain ampicillin fails because the bacterial enzyme breaks it down, while the cephalosporins listed are reserved as second-line. Therefore the first-line treatment is dicloxacillin.
\[\boxed{\text{Dicloxacillin}}\]
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