The right choice to finish the sentence is “which.”
Thus, the full sentence is: “There are many inventions of science which have benefitted human beings in many ways.”
The word “which” introduces a relative clause, giving more detail about the inventions.
Using “which” properly connects the clause to the noun “inventions,” identifying the specific inventions with benefits.
The other choices, “those” and “such,” are grammatically incorrect here as relative pronouns introducing clauses.