Question:easy
Filgrastim is used in the treatment of:
Filgrastim is used in the treatment of:
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It is recombinant G-CSF, so it boosts the neutrophil line.
Updated On: Jun 23, 2026
- Anemia
- Neutropenia
- Malaria
- Filarial
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: The key to this item is recognising what cell line a given growth factor supports. Filgrastim is the recombinant form of granulocyte colony-stimulating factor.
Step 2: By acting on committed granulocyte progenitors, it drives the bone marrow to manufacture and discharge neutrophils. Its headline indication is therefore the correction of a low neutrophil count, especially after cytotoxic chemotherapy.
Step 3: Structurally it is a 175-residue glycoprotein that is non-glycosylated and bears an additional methionine at the N-terminus, yet it retains full biological activity against neutropenia.
Step 4: The distractors map to other therapies: anemia calls for erythropoietin, while malaria and filariasis need antimalarials and antifilarial agents respectively. None of these are colony-stimulating-factor targets.
\[\boxed{\text{Neutropenia}}\]
Step 2: By acting on committed granulocyte progenitors, it drives the bone marrow to manufacture and discharge neutrophils. Its headline indication is therefore the correction of a low neutrophil count, especially after cytotoxic chemotherapy.
Step 3: Structurally it is a 175-residue glycoprotein that is non-glycosylated and bears an additional methionine at the N-terminus, yet it retains full biological activity against neutropenia.
Step 4: The distractors map to other therapies: anemia calls for erythropoietin, while malaria and filariasis need antimalarials and antifilarial agents respectively. None of these are colony-stimulating-factor targets.
\[\boxed{\text{Neutropenia}}\]
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