Remember the three fermentation modes:
\[
\boxed{\text{Batch}=\text{No feeding}}
\]
\[
\boxed{\text{Fed-Batch}=\text{Controlled substrate addition}}
\]
\[
\boxed{\text{Continuous}=\text{Continuous feeding and culture removal}}
\]
Fed-batch fermentation is widely used in industrial production of antibiotics, enzymes, and recombinant proteins.