Equation of the plane through the mid-point of the line segment joining the points P(4, 5, -10) and Q(-1, 2, 1) and perpendicular to PQ is:
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The normal vector of a plane determines the coefficients of $x, y,$ and $z$. If the plane is perpendicular to $PQ$, the coefficients must be proportional to the differences in coordinates of $P$ and $Q$.