Question:medium

Describe the following:
(a) Describe the life cycle of HIV from the time of its entry into the human body till full blown AIDS sets in.

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HIV attacks the immune system, specifically CD4+ Tcells, leaving the body vulnerable to infections.
Updated On: Jan 13, 2026
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Solution and Explanation

Entry: HIV gains entry into host cells (specifically CD4+ T-cells) utilizing surface receptors. Reverse Transcription: Viral RNA undergoes conversion to DNA, facilitated by the enzyme reverse transcriptase. Integration: Viral DNA is integrated into the host cell's genome through the action of the integrase enzyme. Replication: The host cell's machinery is employed to synthesize viral components. Assembly and Release: New viral particles are constructed and subsequently released, enabling the infection of additional cells. Progression to AIDS: Persistent depletion of CD4+ cells results in compromised immunity and susceptibility to opportunistic infections, ultimately leading to the development of AIDS.
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