Step 1: Read the question as a false-statement hunt about DVT and test each option against what we know of the disease.
Step 2: Real DVT almost always affects one leg. Every limb-specific item in the Wells score - unilateral oedema, calf swelling measured against the other side, swollen superficial veins on the symptomatic leg - is built around that one-sidedness.
Step 3: Therefore the claim that DVT is mostly bilateral contradicts its core clinical picture and is the incorrect statement.
Step 4: By contrast, calf pain with tenderness is the usual presentation, a silent DVT can first surface as pulmonary embolism, and the Wells-based clinical assessment is a recognised reliable screen - all true. The odd one out is bilateral.
\[\boxed{\text{Mostly bilateral}}\]