Question

Conversion of a complete hydatidiform mole into an invasive mole is indicated by all of the following except:

• A. Plateau in hCG
• B. Enlarged uterine size
• C. Persistence of theca lutein cysts
• D. Suburethral nodule

Hint:

Plateauing hCG, a bulky uterus and persistent theca lutein cysts all warn of conversion.

Answer 1

The Correct Option is D

The stem lists four findings and asks which one does NOT flag progression of a complete mole to an invasive mole, so confirm the three real markers and the leftover is the answer.

The cleanest marker is the hCG trend. After a mole is evacuated, the hormone should fall steadily to zero. If the level stalls and plateaus across several weekly readings, trophoblastic tissue is still active and invading, so a plateau in hCG is a true warning sign.

Uterine size is the second marker. A uterus that stays enlarged or grows again after evacuation reflects retained, invasive trophoblast rather than normal involution, so this too signals conversion.

Theca lutein cysts are the third marker. These ovarian cysts are driven by high hCG, so their persistence means hCG remains elevated and disease continues, again pointing to invasive mole.

That leaves the suburethral nodule, which is not a standard indicator of a complete mole turning invasive. It is therefore the exception the question wants.

$Plateau\ hCG + persistent\ uterine\ enlargement + persistent\ theca\ lutein\ cysts\ indicate\ conversion;\ the\ nodule\ does\ not$
\[\boxed{Suburethral\ nodule}\]