Question

Consider the following and choose the correct answer Assertion [A]: MHC Class I presents endogenous antigens to CD8\(^+\) T cells. Reason [R]: Endogenous peptides are generated in lysosomes. The correct answer is

• A. Both [A] and [R] are true and [R] is the correct explanation of [A]
• B. Both [A] and [R] are true and [R] is not the correct explanation of [A]
• C. [A] is true, but [R] is false
• D. [A] is false, but [R] is true

Hint:

Antigen processing pathways: \[ \boxed{ \begin{aligned} \text{MHC Class I} &\rightarrow \text{Proteasome} \rightarrow \text{CD8}^{+}\text{ T cells} \text{MHC Class II} &\rightarrow \text{Lysosome} \rightarrow \text{CD4}^{+}\text{ T cells} \end{aligned} } \]

Answer 1

The Correct Option is C