Question:medium
Chordoma arises from:
Chordoma arises from:
Updated On: Jun 24, 2026
- Pharyngeal bursa
- Notochord
- Rathke’s pouch
- Luschka's bursa
Show Solution
The Correct Option is B
Solution and Explanation
Step 1: Trace the embryological origin. The notochord is the midline structure of the developing axial skeleton, and its leftover cells can later become a tumor.
Step 2: These notochordal remnants persist along the midline from the skull base to the sacrum, which is exactly where chordomas appear, most often at the clivus and the sacrum.
Step 3: Histologically, the tumor is divided into conventional, chondroid, and dedifferentiated subtypes, all sharing the notochordal origin.
Step 4: Rathke's pouch is the embryological source of craniopharyngioma, while the pharyngeal and Luschka bursae are unrelated to this tumor. Hence chordoma arises from the notochord.
\[\boxed{\text{Notochord}}\]
Step 2: These notochordal remnants persist along the midline from the skull base to the sacrum, which is exactly where chordomas appear, most often at the clivus and the sacrum.
Step 3: Histologically, the tumor is divided into conventional, chondroid, and dedifferentiated subtypes, all sharing the notochordal origin.
Step 4: Rathke's pouch is the embryological source of craniopharyngioma, while the pharyngeal and Luschka bursae are unrelated to this tumor. Hence chordoma arises from the notochord.
\[\boxed{\text{Notochord}}\]
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