Question:medium

Choose the antigenic component of the viral infection Hepatitis B from the following options.

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Hepatitis B vaccine = recombinant HBsAg + alum adjuvant, providing protection without live virus.
Updated On: Feb 19, 2026
  • Alum-adsorbed inactivated Hepatitis B surface antigen
  • Alum-adsorbed recombinant Hepatitis B surface antigen
  • Inactivated trivalent WHO-recommended strains
  • Attenuated trivalent WHO-recommended strains
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The Correct Option is B

Solution and Explanation

Step 1: Hepatitis B Vaccine Composition.
The Hepatitis B vaccine is a subunit vaccine, not live. It utilizes purified surface antigen (HBsAg) produced via recombinant DNA technology in yeast.
Step 2: Adjuvant Function.
To bolster the immune response, the recombinant HBsAg is adsorbed onto alum (aluminum hydroxide). This adjuvant improves antigen presentation and antibody generation.
Step 3: Discarding Incorrect Choices.
- (A) Incorrect: The vaccine is recombinant, not an inactivated surface antigen.
- (C) and (D) Incorrect: These refer to influenza vaccines, not Hepatitis B.
Step 4: Identifying the Correct Component.
Therefore, the accurate component is alum-adsorbed recombinant Hepatitis B surface antigen.
Final Answer:
\[\boxed{\text{Alum-adsorbed recombinant Hepatitis B surface antigen}}\]
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