Question:medium
Causes of primary amenorrhoea are all of the following except?
Causes of primary amenorrhoea are all of the following except?
Show Hint
One of these only happens after a postpartum haemorrhage.
Updated On: Jun 24, 2026
- Rokitansky syndrome (Mayer-Rokitansky-Kuster-Hauser syndrome)
- Kallmann syndrome
- Sheehan syndrome
- Turner syndrome
Show Solution
The Correct Option is C
Solution and Explanation
Sort these syndromes by timing, because primary amenorrhoea means menses never arrived, so the cause has to predate puberty. Mayer-Rokitansky-Kuster-Hauser is a developmental defect where the uterus and upper vagina simply did not form, so there is no endometrium to shed from the very start. Kallmann is a failure of GnRH neurons to migrate, present at birth and joined by loss of smell, which keeps the hypothalamic-pituitary-ovarian axis switched off from the beginning. Turner syndrome carries a missing X, leaving streak ovaries that cannot drive puberty, again a congenital cause. Sheehan syndrome breaks this pattern entirely: it is destruction of the anterior pituitary by ischaemia after a massive postpartum bleed. A woman can only develop it once she has already been pregnant and delivered, which means she had functioning menses beforehand. Loss of periods after that event is secondary amenorrhoea, so Sheehan does not belong in a list of primary amenorrhoea causes.
\[\boxed{\text{Sheehan syndrome}}\]
\[\boxed{\text{Sheehan syndrome}}\]
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