Question

Match List I with List II :

List I (Bioactive molecules)   List II (Importance)
A. Streptokinase               I. Immunosuppressive agent
B. Statins                     II. Removal of clots from the blood vessels
C. Lipases                     III. Blood cholesterol-lowering agent
D. Cyclosporin A               IV. Detergent formulations

Choose the correct answer from the options given below :

• A. A-II, B-III, C-I, D-IV
• B. A-IV, B-III, C-II, D-I
• C. A-II, B-III, C-IV, D-I
• D. A-III, B-II, C-IV, D-I

Hint:

Logic Tip: Use functional word associations: \textbf{Strep}tokinase = \textbf{Stops} clots. \textbf{Stat}ins = Keeps cholesterol \textbf{Static}/Low. \textbf{Lip}ase = Breaks down \textbf{Lip}ids (oils/fats in laundry). \textbf{Cyclo}sporin = \textbf{Cycles} down the immune system.

Answer 1

The Correct Option is C

Step 1 : Understanding the Question:
This matching question focuses on "Microbes in Human Welfare." We need to link specific bioactive molecules or enzymes with their respective clinical or industrial uses.
Step 2 : Key Formulas and Approach:
The approach relies on associating each chemical with its biological action:
1. Streptokinase: Fibrinolytic (clot buster).
2. Statins: HMG-CoA reductase inhibitors (cholesterol).
3. Lipases: Lipid breakdown.
4. Cyclosporin A: T-cell suppression.
Step 3 : Detailed Explanation:

Streptokinase (A): Produced by the bacterium {Streptococcus}, it is used as a "clot buster" to dissolve blood clots in patients who have suffered a myocardial infarction. Thus, A matches with II.

Statins (B): Produced by the yeast {Monascus purpureus}, statins competitively inhibit the enzyme responsible for cholesterol synthesis. They act as blood cholesterol-lowering agents. Thus, B matches with III.

Lipases (C): These are enzymes that digest lipids (oils and fats). They are used in detergent formulations to effectively remove oily stains from laundry. Thus, C matches with IV.

Cyclosporin A (D): Produced by the fungus {Trichoderma polysporum}, this molecule is a potent immunosuppressive agent used to prevent organ rejection in transplant patients. Thus, D matches with I.

Step 4 : Final Answer:
The correct matching sequence is A-II, B-III, C-IV, and D-I. This is represented in option (C).