Question

(b) “DNA replication is continuous and discontinuous on the two strands within the replication fork.” Explain with the help of a schematic representation.

Hint:

The semi-discontinuous replication mechanism ensures efficient and accurate duplication of genetic material.

Answer 1

- Leading strand: Continuously synthesized 5’ to 3’ towards the replication fork.
- Lagging strand: Synthesized 5’ to 3’ in short Okazaki fragments, moving away from the replication fork. DNA ligase subsequently joins these fragments to maintain strand continuity.