Question

Assertion (A): The p53 gene is often called guardian angel of human genome. Reason (R): It inhibits the development of tumors.

• A. Both (A) and (R) are true. (R) is the correct explanation for (A)
• B. Both (A) and (R) are true. (R) is not the correct explanation for (A)
• C. (A) is true. But (R) is false
• D. (A) is false. But (R) is true

Hint:

p53: Guards the genome by stopping tumors!

Answer 1

The Correct Option is A

Step 1: Read both parts.
Assertion (A) says the p53 gene is often called the guardian angel of the human genome. Reason (R) says it stops tumors from forming. We judge both and check the link.

Step 2: Check the Assertion.
The p53 gene watches over the cell's DNA. If the DNA is damaged, p53 pauses cell division to allow repair, or pushes the cell to die if the damage is too great. Because of this protective role, it is nicknamed the guardian of the genome. So (A) is true.

Step 3: Check the Reason.
The p53 gene is a tumor suppressor gene. By stopping damaged cells from dividing wildly, it prevents tumors from growing. So (R) is true.

Step 4: Link the two ideas.
The reason p53 earns the guardian name is exactly that it blocks dangerous cell growth and stops tumors. So the two statements are tied together.

Step 5: Confirm the explanation.
Since stopping tumors is the very reason p53 protects the genome, (R) clearly explains (A).

Step 6: Choose the option.
Both are true and the reason is the correct explanation of the assertion.
\[ \boxed{\text{Both (A) and (R) are true. (R) is the correct explanation for (A)}} \]