Question:easy
Apixaban is -
Apixaban is -
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The -xaban suffix marks a direct factor Xa inhibitor.
Updated On: Jun 23, 2026
- Antithrombin inhibitor
- Direct Xa inhibitor
- Platelet activator
- Clotting Factor XII
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The Correct Option is B
Solution and Explanation
Step 1: Use the -xaban suffix as a memory cue. Drugs ending in xaban (apixaban, rivaroxaban, edoxaban) are direct factor $Xa$ inhibitors.
Step 2: Apixaban binds the active site of factor $Xa$ directly, without needing antithrombin as a cofactor. Less factor $Xa$ activity means less thrombin produced and a weaker clot.
Step 3: This pharmacology underlies its approved uses: preventing and treating DVT and pulmonary embolism and preventing stroke in non-valvular atrial fibrillation. The matching label is therefore direct $Xa$ inhibitor.
Step 4: Exclude the rest. Antithrombin-dependent action describes heparin, a platelet activator would be prothrombotic (the opposite of intent), and factor XII is a coagulation factor, not a drug class.
\[\boxed{Direct\ Xa\ inhibitor}\]
Step 2: Apixaban binds the active site of factor $Xa$ directly, without needing antithrombin as a cofactor. Less factor $Xa$ activity means less thrombin produced and a weaker clot.
Step 3: This pharmacology underlies its approved uses: preventing and treating DVT and pulmonary embolism and preventing stroke in non-valvular atrial fibrillation. The matching label is therefore direct $Xa$ inhibitor.
Step 4: Exclude the rest. Antithrombin-dependent action describes heparin, a platelet activator would be prothrombotic (the opposite of intent), and factor XII is a coagulation factor, not a drug class.
\[\boxed{Direct\ Xa\ inhibitor}\]
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