Question:hard
All of the following may be associated with thymoma, except:
All of the following may be associated with thymoma, except:
Show Hint
SIADH belongs to small cell lung cancer; thymoma links to myasthenia, Good syndrome, and ectopic ACTH.
Updated On: Jun 24, 2026
- SIADH
- Myasthenia gravis
- Hypogammaglobulinemia
- Cushing's syndrome
Show Solution
The Correct Option is A
Solution and Explanation
Treat this as a find the outlier task. Three of the four are genuine thymoma associations and one is not.
Myasthenia gravis tops the list. Anti acetylcholine receptor antibodies link it tightly to thymoma, and removing the thymus often helps, so option B belongs.
Hypogammaglobulinemia is the next true association, recognised as Good syndrome, in which a thymoma coexists with depressed antibody levels and recurrent infections, so option C belongs.
Cushing's syndrome can arise when a thymic neuroendocrine or carcinoid tumour pumps out ectopic ACTH, so option D belongs.
That leaves SIADH. Inappropriate antidiuretic hormone release is the signature paraneoplastic effect of small cell lung cancer, not of thymic tumours. Thymoma is not a recognised cause of SIADH, so option A is the exception.
\[\boxed{\text{SIADH}}\]
Myasthenia gravis tops the list. Anti acetylcholine receptor antibodies link it tightly to thymoma, and removing the thymus often helps, so option B belongs.
Hypogammaglobulinemia is the next true association, recognised as Good syndrome, in which a thymoma coexists with depressed antibody levels and recurrent infections, so option C belongs.
Cushing's syndrome can arise when a thymic neuroendocrine or carcinoid tumour pumps out ectopic ACTH, so option D belongs.
That leaves SIADH. Inappropriate antidiuretic hormone release is the signature paraneoplastic effect of small cell lung cancer, not of thymic tumours. Thymoma is not a recognised cause of SIADH, so option A is the exception.
\[\boxed{\text{SIADH}}\]
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