Question:medium
All of the following factors contribute to resurgence of malaria, except:
All of the following factors contribute to resurgence of malaria, except:
Show Hint
Drugs act on the parasite, not the host, so host drug resistance is meaningless.
Updated On: Jun 24, 2026
- Drug resistance in host
- Drug resistance in parasite
- Drug resistance in vectors
- Antigenic variations in parasite
Show Solution
The Correct Option is A
Solution and Explanation
Picture malaria coming back after it had been pushed down. The forces behind such a comeback are partly programme failures and partly biology. On the biological side, the parasite can learn to survive the drugs we give, and the mosquito can learn to survive the insecticides we spray. The parasite can also change its surface antigens to slip past the immune system, keeping transmission alive.
So drug resistance arising in the parasite is a genuine driver, insecticide resistance in the mosquito vector is a genuine driver, and antigenic variation in the parasite is a genuine driver.
The phrase that does not make sense is resistance to antimalarial drugs developing in the human host. People do not become drug resistant; it is the parasite that becomes drug resistant and the vector that becomes insecticide resistant. That mislabelled option is therefore the exception.
\[\boxed{\text{Drug resistance in host}}\]
So drug resistance arising in the parasite is a genuine driver, insecticide resistance in the mosquito vector is a genuine driver, and antigenic variation in the parasite is a genuine driver.
The phrase that does not make sense is resistance to antimalarial drugs developing in the human host. People do not become drug resistant; it is the parasite that becomes drug resistant and the vector that becomes insecticide resistant. That mislabelled option is therefore the exception.
\[\boxed{\text{Drug resistance in host}}\]
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