Question:medium
All of the following are common sites of primary tumour for bone metastasis EXCEPT:
All of the following are common sites of primary tumour for bone metastasis EXCEPT:
Show Hint
Recall the BLT-KP primaries; the central nervous system primary is the odd one.
Updated On: Jun 24, 2026
- Breast
- Prostate
- Brain
- Lung
Show Solution
The Correct Option is C
Solution and Explanation
Step 1: The stem asks which organ is NOT a usual origin of cancer that seeds the skeleton. Skeletal metastases are the most common bone malignancy and travel mainly via blood.
Step 2: The five well-known bone-seeking primaries are breast, lung, thyroid, kidney and prostate. Breast tops the list overall and prostate leads in men, so options of breast, prostate and lung all qualify as common sources.
Step 3: Primary brain tumours behave very differently. They tend to stay within the cranial vault and only exceptionally spread to bone, so the brain does not belong among common primaries for bone metastasis.
Step 4: Eliminating the bone-seeking primaries leaves the brain as the odd one out, which is exactly the answer the EXCEPT format requires.
\[\boxed{\text{Brain}}\]
Step 2: The five well-known bone-seeking primaries are breast, lung, thyroid, kidney and prostate. Breast tops the list overall and prostate leads in men, so options of breast, prostate and lung all qualify as common sources.
Step 3: Primary brain tumours behave very differently. They tend to stay within the cranial vault and only exceptionally spread to bone, so the brain does not belong among common primaries for bone metastasis.
Step 4: Eliminating the bone-seeking primaries leaves the brain as the odd one out, which is exactly the answer the EXCEPT format requires.
\[\boxed{\text{Brain}}\]
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