Question:easy

After kidney transplantation, infection with which organism is most likely to occur?

Show Hint

Think latent virus reactivating under T-cell suppression.
Updated On: Jun 23, 2026
  • CMV
  • Klebsiella
  • Streptococcus
  • Staphylococcus
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The Correct Option is A

Solution and Explanation

Step 1: The key is the type of immune defect after a kidney transplant - drug-induced suppression of cell-mediated immunity, which uncovers latent viruses. Step 2: The classic opportunist that emerges is $Cytomegalovirus$, the most frequent viral infection of renal transplant recipients, peaking around 1-4 months post-transplant. Step 3: Recognise its syndrome: fever as the leading sign, plus leukopenia, hepatosplenomegaly and myalgias/arthralgias. Step 4: The bacterial options (Klebsiella, Streptococcus, Staphylococcus) are ordinary nosocomial bugs, not the signature transplant pathogen, so CMV is selected. \[\boxed{\text{CMV}}\]
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