- Scientist: Frederick Griffith.
- Experiment:
1. He studied the bacterium \( \textit{Streptococcus pneumoniae} \), differentiating between the virulent S strain and the non-virulent R strain.
2. When heat-killed S strain bacteria were combined with live R strain bacteria, the R strain transformed into a virulent S strain.
- Conclusion:
- A "transforming principle," subsequently identified as DNA, was determined to be responsible for genetic stability and the transmission of traits.